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Intrathecal Drug Delivery with the SynchroMed® System

 

Who can benefit from Intrathecal Drug Delivery?

 

Intrathecal Drug Delivery with SynchroMed®

 

Proven benefits

 

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SynchroMed® Infusion System

 

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Proven benefits

  • Good-to-excellent long-term pain relief
    - Excellent or good pain relief scores (mean 61%) reported in 95% of 429 patients over
       a period of 8-94 months [1]
 

 

- 74% of 120 patients benefited from intrathecal therapy over a period of 0.5-5.7 years.
   After a mean follow-up of 3.4 years, 58% of patients reported reduced pain [2]

 

  - 77% of 26 patients reported good-to-excellent pain relief over an average of 23 months [3]

 
  • Enhanced performance of activities of daily living (ADL)
    - 50% average improvement in daily functioning in 26 patients [3]
    - Substantial increases in ADL; 57% moderate or great increase;
       82% some increase [1]
    - Quality of life indicators significantly improved in patients with non-malignant
       pain 1 year after implants [4]
    - 81% of 120 patients were satisfied with therapy received [2]
  • High patient satisfaction
    - 92% of 120 patients reported improved quality of life [5]
  • Reduced side-effects
    - Dose can be reduced to as little as 1/300th of the oral dose [6]
    - Fewer side-effects compared with other doses of administration [1,2,6,7,8]
    - Less sedation and constipation resulting in increased quality of life [7]
    - Minimal likelihood of opioid addiction or tolerance [9]
  • Reduced oral medication intake
    - Significant reduction in oral medication intake in 88 patients (63% with FBS)
       who had experienced chronic pain for 9.8 years [10]

References

1. Paice J. J Pain Symptom Manage 1996; 11:71-80
2. Winkelmuller M. J Neurosurg 1996; 85:458-467
3. Tutak V. South Med J 1996; 89:295-300
4. Mueller-Schwefe G. Neuromodulation 1999; 2:77-84
5. Ohnmeiss DD. Spine J 2001; 1:358-363
6. Krames ES. J Pain Symptom Manage 1996; 11:333-352
7. Gianino JM. Practical Patient Management 1996:127-154
8. Naumann C. Neuromodulation 1999; 2:92-107
9. Portenoy RK. J Pain Symptom Manage 1997; 14:S27-35
10. Roberts. Eur J Pain 2001; 5(A):353-361



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