A Highly Lipophilic Sirolimus Analogue
Designed to Inhibit Smooth Muscle Cell Proliferation
Complete Drug Elution
I. Endeavor System Key Benefits
II. Endeavor Design
III. Endeavor Stent Clinical Trials
V. Resources
Contact
ABT-578: A Highly Lipophilic Sirolimus
ABT-578 is a tetrazole-containing sirolimus analogue. It is proposed that ABT-578 binds with FKBP12 to interfere with mTOR (mammalian target of rapamycin/sirolimus)
*Test data on file at Medtronic, Inc.