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Medtronic Home > Information for Physicians > Treatment of CAD > ABT-578: A Highly Lipophilic Sirolimus
  ABT-578 Drug
 

A Highly Lipophilic Sirolimus Analogue

 

Designed to Inhibit Smooth Muscle Cell Proliferation

 

Complete Drug Elution

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  Treatment of CAD
 

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II. Endeavor Design

 

III. Endeavor Stent Clinical Trials

 

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ABT-578: A Highly Lipophilic Sirolimus

ABT-578 is a tetrazole-containing sirolimus analogue. It is proposed that ABT-578 binds with FKBP12 to interfere with mTOR (mammalian target of rapamycin/sirolimus)

*Test data on file at Medtronic, Inc.



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