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Rebecca Fancini, Public and Media Relations , +44 1923 212 213

NEUROMODULATION


What Is Neuromodulation?

Which Patients Benefit From It?

How Does Neuromodulation Work?

The Benefits Of Neuromodulation

References

1 Kemler MA, Barendse GA, Van Kleef et al.  Spinal cord stimulation in patients with chronic reflex sympathetic dystrophy.  N Engl J Med. 2000; 343 (9):618-624

2 Limousin P et al. Multicentre European study of thalamic stimulation in parkinsonian and essential tremor. Journal of Neurology, Neurosurgery and Psychiatry. 1999;66:289-296

3 Medtronic, Synergy Neuromodulation System 2005.

4 Mobbs RJ et al. Peripheral nerve stimulation for the treatment of chronic pain. Journal of clinical neuroscience. 2007; 14 (3): 216-221

5 Kumar K, Toth C, Nath RK et al.  Epidural spinal cord stimulation for treatment of chronic pain – some predictors of success.  A 15 year experience. Surgical Neurology. 1998;50:110-21

6 Burchiel K, Anderson V et al. Prospective, multicenter study of spinal cord stimulation for relief of chronic back and extremity pain.  Spine. 1996;21:2786-2794

7 Barolat G, Oakley J, Law JD et al.  Epidural spinal cord stimulation for failed back surgery syndrome.  Neuromodulation. 2001; 4: 1

8 Kemler MA, Henrica CW et al. The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: Two years’ follow-up of the randomised controlled trial. Annals of Neurology. 2004;55:13-18

9 Van Buyten JP, Van Zundert J, Vueghs P, Vanduffel L. Efficacy of spinal cord stimulation: 10 years of experience in a pain centre in Belgium.  European Journal of Pain. 2001;5:299-307

10 Krack P, Batir A, Blercome N et al, Five-Year Follow-up of Bilateral Stimulation of the Subthalamic Nucleus in Advanced Parkinson’s Disease, New England Medical Journal. 2003;349(13): 1925-1934

11 Sydow O, Thobois S, Alesch F, Speelman JD. Multicentre European study of thalamic stimulation in essential tremor: a six year follow-up. J Neurol Neurosurg Psychiatry. 2003; 74:1387-1391

12 Vidailhet M, Vercueil L, Houeto JL, Krystkowiak P, Lagrange C, Yelnik J et al. Bilateral, pallidal, deep-brain stimulation in primary generalised dystonia: a prospective 3 year follow-up study. Lancet Neurol. 2007; 6: 223-229


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